New research has raised significant concerns about the safety of certain herbal supplements popularized on TikTok. Researchers at the University of Michigan have identified six supplements, including Ashwagandha, Green Tea Extract, and Garcinia cambogia, as potentially hepatotoxic. This finding suggests that these widely-used products may cause liver damage, a risk that becomes more pronounced when consumed in high doses.
The study highlights the possible link between excessive catechin accumulation in the liver and its harmful effects. Catechins, antioxidants found in green tea, are believed to cause oxidative damage and inflammation, leading to various liver-related issues. While the precise mechanism remains unclear, researchers report that the liver damage risk is dose-dependent and could lead to severe conditions such as hepatitis and liver failure.
The risk of liver damage is not limited to the supplements themselves. These products may also interact with other medications, further increasing the potential for adverse effects. The National Center for Complementary and Integrative Health (NCCIH) echoes these findings, emphasizing the lack of robust research supporting any health benefits from these supplements. They advise consulting healthcare providers before starting any new herbal regimen, particularly for individuals with a history of liver disease or on medication.
“It contains compounds known as monacolins, which are similar to statins and may help lower cholesterol levels,” Tejada explains.
“Red yeast rice may cause elevated liver enzymes, liver inflammation, and, in rare cases, acute liver failure,” Tejada notes.
Beyond liver damage, these supplements are associated with other side effects such as stomach upset, diarrhea, and headaches. Although the prevalence of liver damage from these supplements appears rare, it remains a serious concern. Furthermore, potential interactions with other supplements or medications could elevate the risk of not only liver damage but also kidney damage, cardiovascular disease, and cancer.
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